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Neuroscientist David Nutt published a piece in the Guardian today detailing a line of research he hopes will lead to an alcohol substitute—one that produces many of the neurological effects of alcohol, with none of the chemical’s direct physical harm.

The key to decoding alcohol is the gamma aminobutyric acid neurotransmitter system in the brain, which regulates the brain and keeps things calm. It’s also the main target of alcohol, which replicates and enhances those calming effects but also not-so-desirable ones like aggression and addiction. However, as it turns out, the “GABA” system isn’t quite that simple.

GABA has several subsystems that can be affected by targeted drugs. With this knowledge in his pocket, Nutt has done what many others would doubtless do in his place: devoted his time to isolating five specific compounds that perform alcohol’s desirable functions without its drawbacks.
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Story: http://gawker.com/this-booze-substitute-and-its-antidote-gets-you-drunk-1462421049